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Literature summary extracted from

  • Rodriguez de la Vega, M.; Sevilla, R.G.; Hermoso, A.; Lorenzo, J.; Tanco, S.; Diez, A.; Fricker, L.D.; Bautista, J.M.; Aviles, F.X.
    Nna1-like proteins are active metallocarboxypeptidases of a new and diverse M14 subfamily (2007), FASEB J., 21, 851-865.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.17.17 ADP
-
 Caenorhabditis elegans
3.4.17.17 ATP
-
 Caenorhabditis elegans

Application

EC Number Application Comment Organism
3.4.17.17 additional information link between tubulinyl-Tyr carboxypeptidase and Nna1-like proteins Caenorhabditis elegans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.17.17 AGBL4 expressed as a fusion protein with a thrombin-cleavable His-tag and a factor Xa-cleavable S-tag at the N-terminus in Escherichia coli BL21-Gold(DE3) cells Caenorhabditis elegans

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.17 additional information enzymatic activity is salt-inactivated Caenorhabditis elegans
3.4.17.17 Z-Glu-Tyr
-
 Caenorhabditis elegans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.17.17 cytosol
-
 Caenorhabditis elegans 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.17.17 Zn2+ zinc ligands Caenorhabditis elegans

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.17 Caenorhabditis elegans
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.17 additional information may have the ability to remove C-terminal Tyr residues from proteins based on both its substrate binding pocket and the loops surrounding the active site pocket. Has enzymatic activity toward small peptides that contain C-terminal hydrophobic groups Caenorhabditis elegans ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.17 AGBL4
-
 Caenorhabditis elegans
3.4.17.17 nervous system nuclear protein induced by axotomy
-
 Caenorhabditis elegans
3.4.17.17 Nna1-like peptidase
-
 Caenorhabditis elegans