Literature summary extracted from

Varma, S.; Shrivastav, A.; Changela, S.; Khandelwal, R.L.
Long-term effects of rapamycin treatment on insulin mediated phosphorylation of Akt/PKB and glycogen synthase activity (2008), Exp. Cell Res., 314, 1281-1291.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.11	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.1.11	Hep-G2 cell	upon rapamycin treatment, the overexpression of constitutively active Akt-1 in Hep-G2 cells leads to an increase in the phosphorylation of Akt (Ser 473) and, an increase in the GS and PP-1 activities, in contrast to a decrease in Akt phosphorylation and GS and PP-1 activities in parental HepG2 cells	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.1.11	UDP-glucose + glycogen	-	Homo sapiens	glycogen + UDP	-	?

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Release 2023.1 (January 2023)