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Literature summary extracted from

  • Lu, X.; Kambe, F.; Cao, X.; Kozaki, Y.; Kaji, T.; Ishii, T.; Seo, H.
    3beta-Hydroxysteroid-DELTA24 reductase is a hydrogen peroxide scavenger, protecting cells from oxidative stress-induced apoptosis (2008), Endocrinology, 149, 3267-3273.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.72 expressed in Mus musculus embryonic fibroblasts and PC-12 cells infected with adenovirus Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.72 endoplasmic reticulum
-
 Mus musculus 5783
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.72 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.72 5alpha-cholesta-7,24-dien-3beta-ol + NADPH
-
 Mus musculus 5alpha-cholest-7-en-3beta-ol + NADP+
-
 ?
1.3.1.72 additional information intracellular generation of reactive oxygen species in response to H2O2 is diminished in the presence of DHCR24, suggesting a reactive oxygen species-scavenging activity of DHCR24 Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.72 3beta-hydroxysteroid-DELTA24 reductase
-
 Mus musculus
1.3.1.72 DHCR24
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.72 NADPH
-
 Mus musculus