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Literature summary extracted from

  • Nobecourt, E.; Zeng, J.; Davies, M.J.; Brown, B.E.; Yadav, S.; Barter, P.J.; Rye, K.A.
    Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I (2008), Diabetologia, 51, 1008-1017.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.43 apolipoprotein A-I the impact of glycation on apolipoprotein A-I structure and its ability to activate LCAT is investigated: The rate of LCAT-mediated cholesterol esterification in reconstituted HDL containing phosphatidylcholine and apoA-I varied according to the level of apoA-I glycation and progressively decreases as the extent of apoA-I glycation increases Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 phosphatidylcholine + cholesterol
-
Homo sapiens 1-acylglycerophosphocholine + cholesteryl ester
-
?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.43 LCAT
-
Homo sapiens
2.3.1.43 lecithin-cholesterol acyltransferase
-
Homo sapiens