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Literature summary extracted from

  • Keilhoff, G.; Prell, T.; Langnaese, K.; Mawrin, C.; Simon, M.; Fansa, H.; Nicholas, A.P.
    Expression pattern of peptidylarginine deiminase in rat and human Schwann cells (2007), Dev. Neurobiol., 68, 101-114.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.3.15 expression analysis Homo sapiens
3.5.3.15 expression analysis Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.3.15 nucleus PAD3, exclusively Homo sapiens 5634
-
3.5.3.15 nucleus PAD3, exclusively Rattus norvegicus 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.15 Ca2+ dependent on Homo sapiens
3.5.3.15 Ca2+ dependent on Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.3.15 protein-L-arginine + H2O Homo sapiens citrullination of proteins may exert a specific role in the course of PNS development and repair protein-L-citrulline + NH3
-
?
3.5.3.15 protein-L-arginine + H2O Rattus norvegicus citrullination of proteins may exert a specific role in the course of PNS development and repair protein-L-citrulline + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.15 Homo sapiens
-
-
-
3.5.3.15 Homo sapiens Q9ULC6 PAD1
-
3.5.3.15 Homo sapiens Q9Y2J8 PAD2
-
3.5.3.15 Rattus norvegicus
-
female and male Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.15 cerebellum
-
Rattus norvegicus
-
3.5.3.15 cerebellum
-
Homo sapiens
-
3.5.3.15 cerebellum high amount of PAD2 Homo sapiens
-
3.5.3.15 dermis
-
Rattus norvegicus
-
3.5.3.15 dermis high amount of PAD2 Homo sapiens
-
3.5.3.15 additional information PAD tissue expression pattern, overview Homo sapiens
-
3.5.3.15 additional information PAD tissue expression pattern, overview Rattus norvegicus
-
3.5.3.15 nerve fetal, increased amounts of PAD3 Homo sapiens
-
3.5.3.15 nerve juvenile, increased amounts of PAD3 Rattus norvegicus
-
3.5.3.15 oligodendrocyte PAD2 Rattus norvegicus
-
3.5.3.15 oligodendrocyte PAD2 Homo sapiens
-
3.5.3.15 Schwann cell
-
Homo sapiens
-
3.5.3.15 Schwann cell majority of PAD2 staining in immature cell stages, overview Rattus norvegicus
-
3.5.3.15 Schwann cell majority of PAD2 staining in immature cell stages, overview Homo sapiens
-
3.5.3.15 sciatic nerve fetal Homo sapiens
-
3.5.3.15 sciatic nerve fetal, increased amounts of PAD2 Homo sapiens
-
3.5.3.15 sciatic nerve juvenile, increased amounts of PAD2 Rattus norvegicus
-
3.5.3.15 skin
-
Rattus norvegicus
-
3.5.3.15 skin
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.15 protein-L-arginine + H2O
-
Homo sapiens protein-L-citrulline + NH3
-
?
3.5.3.15 protein-L-arginine + H2O
-
Rattus norvegicus protein-L-citrulline + NH3
-
?
3.5.3.15 protein-L-arginine + H2O citrullination of proteins may exert a specific role in the course of PNS development and repair Homo sapiens protein-L-citrulline + NH3
-
?
3.5.3.15 protein-L-arginine + H2O citrullination of proteins may exert a specific role in the course of PNS development and repair Rattus norvegicus protein-L-citrulline + NH3
-
?

Synonyms

EC Number Synonyms Comment Organism
3.5.3.15 PAD
-
Homo sapiens
3.5.3.15 PAD
-
Rattus norvegicus
3.5.3.15 peptidylarginine deiminase
-
Homo sapiens
3.5.3.15 peptidylarginine deiminase
-
Rattus norvegicus