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Literature summary extracted from

  • Sorokina, N.; ODonnell, J.M.; McKinney, R.D.; Pound, K.M.; Woldegiorgis, G.; LaNoue, K.F.; Ballal, K.; Taegtmeyer, H.; Buttrick, P.M.; Lewandowski, E.D.
    Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts (2007), Circulation, 115, 2033-2041.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.21 medicine hypertrophied myocardium displays a significant shift in the relative isoform distribution of CPT1 isoforms, L-CPT1 expression dramatically increases relative to M-CPT1 expression Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrion
-
 Rattus norvegicus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 75000
-
 determined by SDS-PAGE and Western Blot analysis Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-palmitoylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
 male Sprague-Dawley rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 carnitine palmitoyltransferase I
-
 Rattus norvegicus