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Literature summary extracted from

  • Yraola, F.; Garcia-Vicente, S.; Marti, L.; Albericio, F.; Zorzano, A.; Royo, M.
    Understanding the mechanism of action of the novel SSAO substrate (C7NH10)6(V10O28).2H2O, a prodrug of peroxovanadate insulin mimetics (2007), Chem. Biol. Drug Des., 69, 423-428.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.21 medicine hexakis(benzylammonium) decavanadate (V) dihydrate acts as a prodrug of peroxovanadate insulin mimetics. SSAO oxidizes hexakis(benzylammonium) decavanadate (V) dihydrate to the same extent as it does benzylamine Mus musculus
1.4.3.21 medicine hexakis(benzylammonium) decavanadate (V) dihydrate acts as a prodrug of peroxovanadate insulin mimetics. SSAO oxidizes hexakis(benzylammonium) decavanadate (V) dihydrate to the same extent as it does benzylamine Homo sapiens
1.4.3.21 medicine hexakis(benzylammonium) decavanadate (V) dihydrate acts as a prodrug of peroxovanadate insulin mimetics. SSAO oxidizes hexakis(benzylammonium) decavanadate (V) dihydrate to the same extent as it does benzylamine Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.21 0.0127
-
 benzylamine 37°C Rattus norvegicus
1.4.3.21 0.014
-
 hexakis(benzylammonium) decavanadate (V) dihydrate 37°C Rattus norvegicus
1.4.3.21 0.061
-
 benzylamine 37°C Mus musculus
1.4.3.21 0.0865
-
 hexakis(benzylammonium) decavanadate (V) dihydrate 37°C Mus musculus
1.4.3.21 0.213
-
 hexakis(benzylammonium) decavanadate (V) dihydrate 37°C Homo sapiens
1.4.3.21 0.287
-
 benzylamine 37°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.21 membrane
-
 Mus musculus 16020
-
1.4.3.21 membrane
-
 Rattus norvegicus 16020
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.21 Homo sapiens
-
 recombinant
-
1.4.3.21 Mus musculus
-
-
-
1.4.3.21 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.21 adipose tissue
-
 Mus musculus
-
1.4.3.21 adipose tissue
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 benzylamine + H2O + O2
-
 Mus musculus benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.21 benzylamine + H2O + O2
-
 Homo sapiens benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.21 benzylamine + H2O + O2
-
 Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.21 hexakis(benzylammonium) decavanadate (V) dihydrate + H2O + O2
-
 Mus musculus ?
-
 ?
1.4.3.21 hexakis(benzylammonium) decavanadate (V) dihydrate + H2O + O2
-
 Homo sapiens ?
-
 ?
1.4.3.21 hexakis(benzylammonium) decavanadate (V) dihydrate + H2O + O2
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.21 SSAO
-
 Mus musculus
1.4.3.21 SSAO
-
 Homo sapiens
1.4.3.21 SSAO
-
 Rattus norvegicus