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Literature summary extracted from
- Cholesterol oxidases act as signaling proteins for the biosynthesis of the polyene macrolide pimaricin (2007), Chem. Biol., 14, 279-290.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.3.6 | extracellular | - |
Streptomyces natalensis | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.3.6 | 55000 | - |
x * 55000, SDS-PAGE | Streptomyces natalensis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.3.6 | additional information | Streptomyces natalensis | cholesterol oxidase is involved in pimaricin biosynthesis | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.3.6 | Streptomyces natalensis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.3.6 | - |
Streptomyces natalensis |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.3.6 | culture medium | - |
Streptomyces natalensis | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.3.6 | 12.15 | - |
- |
Streptomyces natalensis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.3.6 | cholesterol + O2 | - |
Streptomyces natalensis | cholest-4-en-3-one + H2O2 | - |
? | |
| 1.1.3.6 | ergosterol + O2 | 22% of the activity with cholesterol | Streptomyces natalensis | ? | - |
? | |
| 1.1.3.6 | additional information | cholesterol oxidase is involved in pimaricin biosynthesis | Streptomyces natalensis | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.3.6 | ? | x * 55000, SDS-PAGE | Streptomyces natalensis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.3.6 | PimE | - |
Streptomyces natalensis |
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Release 2023.1 (January 2023)
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