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Literature summary extracted from

  • Nesbitt, N.M.; Sampson, N.S.
    Antifungal tradecraft by cholesterol oxidase (2007), Chem. Biol., 14, 238-241.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.3.6 cholesterol + O2 Streptomyces natalensis cholesterol oxidase is required for the biosynthesis of the antifungal polyene pimaricin cholest-4-en-3-one + H2O2
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?

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.6 Streptomyces natalensis
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-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.6 cholesterol + O2
-
Streptomyces natalensis cholest-4-en-3-one + H2O2
-
?
1.1.3.6 cholesterol + O2 cholesterol oxidase is required for the biosynthesis of the antifungal polyene pimaricin Streptomyces natalensis cholest-4-en-3-one + H2O2
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?

Synonyms

EC Number Synonyms Comment Organism
1.1.3.6 PimE
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Streptomyces natalensis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.3.6 FAD
-
Streptomyces natalensis