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Literature summary extracted from

  • Asaga, H.; Ishigami, A.
    Microglial expression of peptidylarginine deiminase 2 in the prenatal rat brain (2007), Cell. Mol. Biol. Lett., 12, 536-544.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.15 Ca2+ dependent on Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.3.15 additional information Rattus norvegicus PAD2 is involved in some processes of neurodegeneration and myelination in the central nervous system ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.15 Rattus norvegicus
-
 Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.15 brain
-
 Rattus norvegicus
-
3.5.3.15 cerebrum embryonal, isozyme expression analysis, PAD2 expression occurs also in 19- to 21-day-old embryos at a developmental stage well before myelination begins, overview Rattus norvegicus
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3.5.3.15 embryo
-
 Rattus norvegicus
-
3.5.3.15 hippocampus embryonal, in the prospective dentate gyrus, microglial marker-negative cells show expression of PAD isozyme 2, but not of isozymes PAD1,3, and 4, overview Rattus norvegicus
-
3.5.3.15 microglia embryonal, in the prospective medulla Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.15 additional information PAD2 is involved in some processes of neurodegeneration and myelination in the central nervous system Rattus norvegicus ?
-
 ?
3.5.3.15 N-alpha-benzoyl-L-arginine + H2O
-
 Rattus norvegicus N-alpha-benzoyl-L-citrulline + NH3
-
 ?
3.5.3.15 N-alpha-benzoyl-L-arginine ethyl ester + H2O
-
 Rattus norvegicus N-alpha-benzoyl-L-citrulline ethyl ester + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.3.15 PAD type 2
-
 Rattus norvegicus
3.5.3.15 PAD2
-
 Rattus norvegicus
3.5.3.15 peptidylarginine deiminase 2
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.3.15 50
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.3.15 7.4
-
 assay at Rattus norvegicus