Literature summary extracted from

Tsimokha, A.S.; Mittenberg, A.G.; Kulichkova, V.A.; Kozhukharova, I.V.; Gause, L.N.; Konstantinova, I.M.
Changes in composition and activities of 26S proteasomes under the action of doxorubicin - apoptosis inductor of erythroleukemic K562 cells (2007), Cell Biol. Int., 31, 338-348.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.4.25.1	doxorubicin	apoptosis inductor doxorubicin increases enzymatic activities, regulates subunit composition, and phosphorylation state of 26S proteasomes	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.25.1	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.25.1	K-562 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.25.1	Bz-Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	?	-	?
3.4.25.1	Bz-DL-Arg-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.25.1	26S proteasome	-	Homo sapiens

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Release 2023.1 (January 2023)