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Literature summary extracted from

  • Kajihara, Y.; Kamitani, T.; Sato, R.; Kamei, N.; Miyazaki, T.; Okamoto, R.; Sakakibara, T.; Tsuji, T.; Yamamoto, T.
    Synthesis of CMP-9-modified-sialic acids as donor substrate analogues for mammalian and bacterial sialyltransferases (2007), Carbohydr. Res., 342, 1680-1688.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.4.3.1 synthesis the Photobacterium sialyltransferase can be used in the synthesis of sialoside analogues having a large substituent at the 9-position of Neu5Ac Photobacterium sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.1 0.05
-
 CMP-9''-phenylacetamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
2.4.3.1 0.051
-
 CMP-9''-benzamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
2.4.3.1 0.098
-
 CMP-9''-phenylhexanamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
2.4.3.1 0.11
-
 CMP-9''-benzamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
2.4.3.1 0.11
-
 CMP-9''-phenylpropionamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
2.4.3.1 0.12
-
 cytidine-5'-monophospho-sialic acid pH 5.0, 37°C Rattus norvegicus
2.4.3.1 0.14
-
 cytidine-5'-monophospho-sialic acid pH 5.0, 37°C Photobacterium sp.
2.4.3.1 0.165
-
 CMP-9''-phenylpropionamido-Neu5Ac pH 5.0, 37°C Rattus norvegicus
2.4.3.1 0.34
-
 CMP-9''-phenylacetamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
2.4.3.1 0.53
-
 CMP-9''-phenylhexanamido-Neu5Ac pH 5.0, 37°C Photobacterium sp.
2.4.3.1 1.8
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-9''-benzamido-Neu5Ac Photobacterium sp.
2.4.3.1 2
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylacetamido-Neu5Ac Rattus norvegicus
2.4.3.1 2.5
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-9''-phenylacetamido-Neu5Ac Photobacterium sp.
2.4.3.1 2.5
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-phenylhexanamido-Neu5Ac Photobacterium sp.
2.4.3.1 2.6
-
 lactose pH 5.0, 37°C, cosubstrate: CMP-phenylpropionamido-Neu5Ac Photobacterium sp.
2.4.3.1 3.6
-
 lactose pH 5.0, 37°C, cosubstrate: cytidine-5'-monophospho-sialic acid Photobacterium sp.
2.4.3.1 4.3
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: cytidine-5'-monophospho-sialic acid Rattus norvegicus
2.4.3.1 5.2
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylhexanamido-Neu5Ac Rattus norvegicus
2.4.3.1 6.8
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-benzamido-Neu5Ac Rattus norvegicus
2.4.3.1 10
-
 N-acetyllactosamine pH 5.0, 37°C, cosubstrate: CMP-9''-phenylpropionamido-Neu5Ac Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Photobacterium sp.
-
-
-
2.4.3.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.1 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-9''-benzamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
2.4.3.1 CMP-9''-benzamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
2.4.3.1 CMP-9''-phenylacetamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
2.4.3.1 CMP-9''-phenylacetamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
2.4.3.1 CMP-9''-phenylhexanamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
2.4.3.1 CMP-9''-phenylhexanamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
2.4.3.1 CMP-9''-phenylpropionamido-Neu5Ac + lactose
-
 Photobacterium sp. ?
-
 ?
2.4.3.1 CMP-9''-phenylpropionamido-Neu5Ac + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?
2.4.3.1 cytidine-5'-monophospho-sialic acid + lactose
-
 Photobacterium sp. ?
-
 ?
2.4.3.1 cytidine-5'-monophospho-sialic acid + N-acetyllactosamine
-
 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.1 6STase
-
 Rattus norvegicus
2.4.3.1 6STase
-
 Photobacterium sp.
2.4.3.1 alpha-(2->6)-sialyltransferase
-
 Rattus norvegicus
2.4.3.1 alpha-(2->6)-sialyltransferase
-
 Photobacterium sp.