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Literature summary extracted from

  • Graham-Cole, C.L.; Thomas, H.D.; Taylor, G.A.; Newell, D.R.; Melton, R.G.; Hesp, R.; Boddy, A.V.
    An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed (2007), Cancer Chemother. Pharmacol., 59, 197-206.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.4 blood plasma
-
Homo sapiens
-
2.4.2.4 colon
-
Homo sapiens
-
2.4.2.4 HT-29 cell
-
Homo sapiens
-
2.4.2.4 kidney
-
Homo sapiens
-
2.4.2.4 liver
-
Homo sapiens
-
2.4.2.4 LoVo cell
-
Homo sapiens
-
2.4.2.4 lung
-
Homo sapiens
-
2.4.2.4 spleen
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.4 deoxyuridine + phosphate
-
Homo sapiens uracil + 2-deoxy-D-ribose 1-phosphate
-
?
2.4.2.4 thymidine + phosphate
-
Homo sapiens thymine + 2-deoxy-D-ribose 1-phosphate
-
?