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Literature summary extracted from

  • Bulhoes, A.C.; Goldani, H.A.; Oliveira, F.S.; Matte, U.S.; Mazzuca, R.B.; Silveira, T.R.
    Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia (2007), Braz. J. Med. Biol. Res., 40, 1441-1446.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.7.1.4 medicine adult-type hypolactasia is characterized by a fall of lactase activity levels to 5 - 10% of birth levels occuring during childhood and adolescence Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.7.1.4 additional information the mutations C/T-13910 and G/A-22018 of the lactase-phlorizin hydrolase gene are correlated with lactose absorption Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.7.1.4 phloretin + H2O Homo sapiens
-
phloretate + phloroglucinol
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.7.1.4 Homo sapiens P09848
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.7.1.4 small intestine intestinal villus Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.7.1.4 lactose + H2O
-
Homo sapiens D-glucose + D-galactose
-
?
3.7.1.4 phloretin + H2O
-
Homo sapiens phloretate + phloroglucinol
-
?

Synonyms

EC Number Synonyms Comment Organism
3.7.1.4 lactase-phlorizin hydrolase
-
Homo sapiens
3.7.1.4 LCT
-
Homo sapiens
3.7.1.4 LPH
-
Homo sapiens
3.7.1.4 phloretin hydrolase
-
Homo sapiens