Literature summary extracted from

Morote-Garcia, J.C.; Rosenberger, P.; Kuhlicke, J.; Eltzschig, H.K.
HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak (2008), Blood, 111, 5571-5580.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.1.20	additional information	Homo sapiens	hypoxia inducible factor 1-alpha-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.20	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.20	microvascular endothelial cell	HMEC-1s	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.20	ATP + ethenoadenosine	-	Homo sapiens	ADP + etheno-AMP	-	?
2.7.1.20	additional information	hypoxia inducible factor 1-alpha-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)