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Literature summary extracted from

  • Liu, L.; Mao, S.Z.; Liu, X.M.; Huang, X.; Xu, J.Y.; Liu, J.Q.; Luo, G.M.; Shen, J.C.
    Functional mimicry of the active site of glutathione peroxidase by glutathione imprinted selenium-containing protein (2008), Biomacromolecules, 9, 363-368.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.9 0.2
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 0.5 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 0.3
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 1 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 0.4
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 2 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 0.45
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 0.5 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 0.62
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 1 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 0.77
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 2 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.9 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.9 H2O2 + GSH
-
 Homo sapiens H2O + GSSG
-
 ?
1.11.1.9 tert-butylhydroperoxide + 3-carboxy-4-nitrobenzenethiol
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.9 GPX
-
 Homo sapiens
1.11.1.9 selenosubtilisin artificial enzyme that imitates the active site of antioxidant selenoenzyme glutathione peroxidase, the imprinted selenium-containing protein exhibits remarkable GPx activity Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.11.1.9 10.55
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 0.5 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 14.48
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 0.5 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 16.02
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 1 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 19.5
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 1 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 20.83
-
 H2O2 apparent value, imprinted GSH-selenosubtilisin in the presence of 2 mM GSH, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens
1.11.1.9 24.5
-
 GSH apparent value, imprinted GSH-selenosubtilisin in the presence of 2 mM H2O2, in 50 mM PIPES buffer, pH 7.0 at 37°C Homo sapiens