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Literature summary extracted from

  • Miyazawa, M.; Tamura, N.
    Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade) (2007), Biol. Pharm. Bull., 30, 595-597.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.18.1 pharmacology (2R,3R)-taxifolin isolated from Benitade may possibly be a of new tyrosinase inhibitor alternative to cosmetic agents such as arbutin and kojic Agaricus bisporus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.18.1 (2R,3R)-taxifolin isolated from the sprout of Polygonum hydropiper L. (Benitade), inhibited 70% of tyrosinase activity at a concentration of 0.50 mM Agaricus bisporus
1.14.18.1 3,7,3',4'-taxifolin tetraacetate assayed together with (2R,3R)-taxifolin Agaricus bisporus
1.14.18.1 5,7,3',4'-taxifolin teramethyl ether assayed together with (2R,3R)-taxifolin Agaricus bisporus
1.14.18.1 arbutin
-
 Agaricus bisporus
1.14.18.1 kojic acid
-
 Agaricus bisporus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.1 Agaricus bisporus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.1 L-tyrosine + O2 + AH2
-
 Agaricus bisporus L-dopa + H2O + A
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.18.1 phenol oxidase
-
 Agaricus bisporus
1.14.18.1 tyrosinase
-
 Agaricus bisporus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.18.1 0.24
-
-
 Agaricus bisporus (2R,3R)-taxifolin