EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.4.53 | - |
Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.53 | diazepam | - |
Mus musculus | |
3.1.4.53 | isobutylmethylxanthine | 0.1 mM, 14% inhibition; 0.1 mM, 32% inhibition | Mus musculus | |
3.1.4.53 | Milrinone | 0.1 mM, 93% inhibition | Mus musculus | |
3.1.4.53 | Ro 20-1724 | 0.1 mM, 12% inhibition; 0.1 mM, 4% inhibition | Mus musculus | |
3.1.4.53 | rolipram | 0.1 mM, 4% inhibition; 0.1 mM, 7% inhibition | Mus musculus | |
3.1.4.53 | zaprinast | 0.1 mM, 67% inhibition; 0.1 mM, 72% inhibition | Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.4.53 | 0.007 | - |
adenosine 3',5'-cyclic phosphate | - |
Mus musculus | |
3.1.4.53 | 0.0092 | - |
adenosine 3',5'-cyclic phosphate | - |
Mus musculus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.4.53 | 83000 | - |
x * 83000, SDS-PAGE | Mus musculus |
3.1.4.53 | 93000 | - |
x * 93000, SDS-PAGE | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.53 | Mus musculus | O89084 | - |
- |
3.1.4.53 | Mus musculus | Q9QXI7 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.53 | adenosine 3',5'-cyclic phosphate + H2O | - |
Mus musculus | adenosine 5'-phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.4.53 | ? | x * 83000, SDS-PAGE | Mus musculus |
3.1.4.53 | ? | x * 93000, SDS-PAGE | Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.4.53 | PDE4A1 | - |
Mus musculus |
3.1.4.53 | PDE4B3 | - |
Mus musculus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.4.53 | 0.0183 | - |
diazepam | - |
Mus musculus | |
3.1.4.53 | 0.0493 | - |
diazepam | - |
Mus musculus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.1.4.53 | 0.00017 | - |
- |
Mus musculus | rolipram | |
3.1.4.53 | 0.0011 | - |
- |
Mus musculus | rolipram | |
3.1.4.53 | 0.0094 | - |
- |
Mus musculus | diazepam | |
3.1.4.53 | 0.043 | - |
- |
Mus musculus | diazepam |