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Literature summary extracted from

  • Burgess, S.G.; Messiha, H.L.; Katona, G.; Rigby, S.E.; Leys, D.; Scrutton, N.S.
    Probing the dynamic interface between trimethylamine dehydrogenase (TMADH) and electron transferring flavoprotein (ETF) in the TMADH-2ETF complex: role of the Arg-alpha237 (ETF) and Tyr-442 (TMADH) residue pair (2008), Biochemistry, 47, 5168-5181.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.8.2 0.0031
-
 alphaR237K mutant electron transferring flavoprotein at 25°C Methylophilus methylotrophus
1.5.8.2 0.0105
-
 electron transferring flavoprotein at 25°C Methylophilus methylotrophus

Organism

EC Number Organism UniProt Comment Textmining
1.5.8.2 Methylophilus methylotrophus
-
-
-
1.5.8.2 Methylophilus methylotrophus W3A1
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.2 additional information does not reduce the alphaR237C, alphaR237E, and alphaR237A mutant electron transferring flavoproteins Methylophilus methylotrophus ?
-
 ?
1.5.8.2 additional information does not reduce the alphaR237C, alphaR237E, and alphaR237A mutant electron transferring flavoproteins Methylophilus methylotrophus W3A1 ?
-
 ?
1.5.8.2 trimethylamine + H2O + alphaR237K mutant electron transferring flavoprotein
-
 Methylophilus methylotrophus dimethylamine + formaldehyde + reduced alphaR237K mutant electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + alphaR237K mutant electron transferring flavoprotein
-
 Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced alphaR237K mutant electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein
-
 Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.8.2 TMADH
-
 Methylophilus methylotrophus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.5.8.2 1.46
-
 alphaR237K mutant electron transferring flavoprotein at 25°C Methylophilus methylotrophus
1.5.8.2 9.67
-
 electron transferring flavoprotein at 25°C Methylophilus methylotrophus

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.8.2 4Fe-4S-center
-
 Methylophilus methylotrophus
1.5.8.2 FAD
-
 Methylophilus methylotrophus