Literature summary extracted from

Tsybovsky, Y.; Donato, H.; Krupenko, N.I.; Davies, C.; Krupenko, S.A.
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases (2007), Biochemistry, 46, 2917-2929.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.5.1.6	expressed in Escherichia coli	Rattus norvegicus

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
1.5.1.6	C-terminal domain of FDH and its complexes with oxidized and reduced forms of NADP+ are crystallized using the hanging drop vapour diffusion method with 1.4-1.5 M ammonium sulfate and 0.1 M Tris-HCl, pH 7.0-7.5	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.6	Rattus norvegicus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.5.1.6	Ni-NTA column chromatography	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.6	10-formyltetrahydrofolate + NADP+ + H2O	-	Rattus norvegicus	tetrahydrofolate + CO2 + NADPH + H+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.5.1.6	10-formyltetrahydrofolate dehydrogenase	-	Rattus norvegicus
1.5.1.6	FDH	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.5.1.6	NADP+	dependent	Rattus norvegicus

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Release 2023.1 (January 2023)