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Literature summary extracted from

  • Amtul, Z.; Follmer, C.; Mahboob, S.; Atta-Ur-Rahman, S.; Mazhar, M.; Khan, K.M.; Siddiqui, R.A.; Muhammad, S.; Kazmi, S.A.; Choudhary, M.I.
    Germa-gamma-lactones as novel inhibitors of bacterial urease activity (2007), Biochem. Biophys. Res. Commun., 356, 457-463.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.5 beta-(o-methoxyphenyl)-gamma,gamma-bis(8-quinolinoxy)germa-gamma-lactone inhibition occurrs in a noncompetitive and concentration-dependent manner. Highly selective in inhibiting the growth of Proteus mirabilis at moderate concentrations. Potential to be developed as antimicrobial agents against Proteus mirabilis infection Proteus mirabilis
3.5.1.5 beta-(o-methylphenyl)-gamma,gamma-bis(8-quinolinoxy)germa-gamma-lactone inhibition occurrs in a noncompetitive and concentration-dependent manner. Highly selective in inhibiting the growth of Proteus mirabilis at moderate concentrations. Potential to be developed as antimicrobial agents against Proteus mirabilis infection Proteus mirabilis

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.5 Proteus mirabilis
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-
-

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.5 0.031
-
-
 Proteus mirabilis beta-(o-methoxyphenyl)-gamma,gamma-bis(8-quinolinoxy)germa-gamma-lactone