Literature summary extracted from

Conterato, G.M.; Augusti, P.R.; Somacal, S.; Einsfeld, L.; Sobieski, R.; Torres, J.R.; Emanuelli, T.
Effect of lead acetate on cytosolic thioredoxin reductase activity and oxidative stress parameters in rat kidneys (2007), Basic Clin. Pharmacol. Toxicol., 101, 96-100.

Application

EC Number	Application	Comment	Organism
1.8.1.9	analysis	thioredoxin reductase-1 may be an early indicator of acute exposure to low lead doses	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.8.1.9	selenium	selenoprotein	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.8.1.9	Rattus norvegicus	O89049	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.8.1.9	kidney	lead exposure causes a marked increase in the thioredoxin reductase-1 activity in the kidney of rats. This is the only parameter affected by low lead doses both after acute and chronic exposure	Rattus norvegicus	-

Synonyms

EC Number	Synonyms	Comment	Organism
1.8.1.9	thioredoxin reductase-1	-	Rattus norvegicus

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Release 2023.1 (January 2023)