EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | apigenin | apigenin reduces cell viability, and induces apoptotic cell death in a dose-dependent manner. In addition, it evokes a dose-related elevation of intracellular reactive oxygen species level. Treatment with various inhibitors of the NADPH oxidase significantly blunts both the generation of reactive oxygen species and induction of apoptosis induced by apigenin | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.3.1 | apocynin | significantly blunts both the generation of reactive oxygen species and induction of apoptosis induced by apigenin | Homo sapiens | |
1.6.3.1 | diphenylene iodonium | significantly blunts both the generation of reactive oxygen species and induction of apoptosis induced by apigenin | Homo sapiens | |
1.6.3.1 | neopterin | significantly blunts both the generation of reactive oxygen species and induction of apoptosis induced by apigenin | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.3.1 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.3.1 | Hep-G2 cell | - |
Homo sapiens | - |