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Literature summary extracted from

  • Yebra, M.J.; Zuniga, M.; Beaufils, S.; Perez-Martinez, G.; Deutscher, J.; Monedero, V.
    Identification of a gene cluster enabling Lactobacillus casei BL23 to utilize myo-inositol (2007), Appl. Environ. Microbiol., 73, 3850-3858.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.2.1.15 additional information iolA is indispensable for myo-inositol fermentation Lacticaseibacillus casei

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.18 gene iolG, encoded and transcribed in the iolTABCDG1G2EJK operon, DNA and amino acid sequence determination and analysis, genetic organization, genes encoded in the iolTABCDG1G2EJK operon transcribe a complete MI catabolic pathway, transcriptional regulation pattern, phalogenetic analysis, overview Lacticaseibacillus casei
1.2.1.15 mutated iolA gene cloned into pRV300 giving pRViolASpeI. Expressed in Lactobacillus casei Lacticaseibacillus casei

Protein Variants

EC Number Protein Variants Comment Organism
1.2.1.15 additional information disruption of iolA gene provides a myo-inositol-negative strain Lacticaseibacillus casei

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.18 Lacticaseibacillus casei
-
 strain BL23, no activity in strain ATCC 334, gene iolG
-
1.2.1.15 Lacticaseibacillus casei
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.15 malonic semialdehyde + NAD+
-
 Lacticaseibacillus casei acetyl-CoA + NADH + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.18 inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase
-
 Lacticaseibacillus casei
1.2.1.15 IolA
-
 Lacticaseibacillus casei