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Literature summary extracted from

  • Lindahl, P.A.
    Implications of a carboxylate-bound C-cluster structure of carbon monoxide dehydrogenase (2008), Angew. Chem., 47, 4054-4056.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.7.4 S2- partial inhibitor Carboxydothermus hydrogenoformans
1.2.7.4 S2- partial inhibitor Neomoorella thermoacetica
1.2.7.4 S2- partial inhibitor Rhodospirillum rubrum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.7.4 Fe2+ contains a NiFe center, called C-cluster Carboxydothermus hydrogenoformans
1.2.7.4 Fe2+ contains a NiFe center, called C-cluster Neomoorella thermoacetica
1.2.7.4 Fe2+ contains a NiFe center, called C-cluster Rhodospirillum rubrum
1.2.7.4 Ni2+ contains a NiFe center, called C-cluster Carboxydothermus hydrogenoformans
1.2.7.4 Ni2+ contains a NiFe center, called C-cluster Neomoorella thermoacetica
1.2.7.4 Ni2+ contains a NiFe center, called C-cluster Rhodospirillum rubrum

Organism

EC Number Organism UniProt Comment Textmining
1.2.7.4 Carboxydothermus hydrogenoformans
-
-
-
1.2.7.4 Neomoorella thermoacetica
-
-
-
1.2.7.4 Rhodospirillum rubrum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.7.4 CO + H2O + acceptor
-
 Carboxydothermus hydrogenoformans CO2 + reduced acceptor
-
 r
1.2.7.4 CO + H2O + acceptor
-
 Rhodospirillum rubrum CO2 + reduced acceptor
-
 r
1.2.7.4 CO + H2O + acceptor
-
 Neomoorella thermoacetica CO2 + reduced acceptor
-
 r

Subunits

EC Number Subunits Comment Organism
1.2.7.4 homodimer
-
 Carboxydothermus hydrogenoformans
1.2.7.4 homodimer
-
 Rhodospirillum rubrum
1.2.7.4 homodimer
-
 Neomoorella thermoacetica

Synonyms

EC Number Synonyms Comment Organism
1.2.7.4 ACS/CODH bifunctional enzyme with ACS alpha subunits and CODH beta subunits Neomoorella thermoacetica
1.2.7.4 CODH
-
 Carboxydothermus hydrogenoformans
1.2.7.4 CODH
-
 Rhodospirillum rubrum