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Literature summary extracted from

  • Szasz, T.; Thompson, J.M.; Watts, S.W.
    A comparison of reactive oxygen species metabolism in the rat aorta and vena cava: focus on xanthine oxidase (2008), Am. J. Physiol. Heart Circ. Physiol., 295, H1341-H1350.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 allopurinol
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 xanthine + H2O + O2 Rattus norvegicus the enzyme is involved in regulation of reactive oxygen species in the functional response of veins and arteries to angiotensin II, norepinephrine, and acetylcholine urate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Rattus norvegicus P22985
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 aorta lower enzyme activity compared to vena cava Rattus norvegicus
-
1.17.3.2 artery
-
 Rattus norvegicus
-
1.17.3.2 vein
-
 Rattus norvegicus
-
1.17.3.2 vena cava higher enzyme activity compared to aorta Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 xanthine + H2O + O2
-
 Rattus norvegicus urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 the enzyme is involved in regulation of reactive oxygen species in the functional response of veins and arteries to angiotensin II, norepinephrine, and acetylcholine Rattus norvegicus urate + H2O2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.17.3.2 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.3.2 7.4
-
 assay at Rattus norvegicus