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Literature summary extracted from
- A complex, tissue-specific role for plasmin and its regulators in modulating fibrogenic activity (2007), Am. J. Physiol., 293, F10-F11.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.21.7 | medicine | role in the course of tissue repair. Plasmin directly influences ERK-mediated signaling leading to epithelial to mesenchymal transition | Mus musculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.7 | alpha2-antiplasmin | - |
Mus musculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.7 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.7 | additional information | tubular epithelial cell | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.7 | Fibrin + H2O | fibrin is broken down through the liberation of plasmin from plasminogen via cleavage by either tissue plasminogen activator and/or urokinase plasminogen activator | Mus musculus | ? | - |
? |  |
| 3.4.21.7 | Fibronectin + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.7 | Laminin + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.7 | additional information | plasmin can activate collagenases | Mus musculus | ? | - |
? | |
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Release 2023.1 (January 2023)
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