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Literature summary extracted from

  • Zhu, D.; Mukherjee, C.; Biehl, E.R.; Hua, L.
    Nitrilase-catalyzed selective hydrolysis of dinitriles and green access to the cyanocarboxylic acids of pharmaceutical importance (2007), Adv. Synth. Catal., 349, 1667-1670.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.5.1 expressed in Escherichia coli Bradyrhizobium japonicum

Organism

EC Number Organism UniProt Comment Textmining
3.5.5.1 Bradyrhizobium japonicum
-
strain USDA110
-
3.5.5.1 Bradyrhizobium japonicum USDA 110
-
strain USDA110
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.5.1 1,4-dicyanobutane + H2O 97% yield Bradyrhizobium japonicum hexanedioic acid + NH3
-
?
3.5.5.1 1,4-dicyanobutane + H2O 97% yield Bradyrhizobium japonicum USDA 110 hexanedioic acid + NH3
-
?
3.5.5.1 1,5-dicyanopentane + H2O 90% yield Bradyrhizobium japonicum heptanedioic acid + NH3
-
?
3.5.5.1 1,6-dicyanohexane + H2O 88% yield Bradyrhizobium japonicum octanedioic acid + NH3
-
?
3.5.5.1 alpha,alpha-dimethylmalononitrile + H2O 93% yield Bradyrhizobium japonicum 2-cyano-2-methylpropanoic acid + NH3
-
?
3.5.5.1 decanedinitrile + H2O 88% yield Bradyrhizobium japonicum 9-cyanononanoic acid + NH3
-
?
3.5.5.1 fumaronitrile + H2O 84% yield Bradyrhizobium japonicum fumaric acid + NH3
-
?
3.5.5.1 fumaronitrile + H2O 84% yield Bradyrhizobium japonicum USDA 110 fumaric acid + NH3
-
?
3.5.5.1 glutaronitrile + H2O 93% yield Bradyrhizobium japonicum glutaric acid + NH3
-
?
3.5.5.1 mandelonitrile + 2 H2O high activity Bradyrhizobium japonicum mandelic acid + NH3
-
?
3.5.5.1 mandelonitrile + 2 H2O high activity Bradyrhizobium japonicum USDA 110 mandelic acid + NH3
-
?
3.5.5.1 additional information nitrilase bll6402 effectively hydrolyzes alpha,omega-dinitriles to omega-cyanocarboxylic acids, and the selectivity is independent of the substrate chain length Bradyrhizobium japonicum ?
-
?
3.5.5.1 additional information nitrilase bll6402 effectively hydrolyzes alpha,omega-dinitriles to omega-cyanocarboxylic acids, and the selectivity is independent of the substrate chain length Bradyrhizobium japonicum USDA 110 ?
-
?
3.5.5.1 succinonitrile + H2O 97% yield Bradyrhizobium japonicum succinic acid + NH3
-
?
3.5.5.1 succinonitrile + H2O 97% yield Bradyrhizobium japonicum USDA 110 succinic acid + NH3
-
?

Synonyms

EC Number Synonyms Comment Organism
3.5.5.1 bll6402
-
Bradyrhizobium japonicum