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Literature summary extracted from

  • Ogiuchi, Y.; Maruoka, Y.; Ando, T.; Kobayashi, M.; Ogiuchi, H.
    Thymidylate synthase, thymidine phosphorylase and orotate phosphoribosyl transferase levels as predictive factors of chemotherapy in oral squamous cell carcinoma (2008), Acta Histochem. Cytochem., 41, 39-46.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.2.4 additional information thymidine phosphorylase demonstrates differential expression depending on age, there is no remarkable difference in the mRNA and protein expression of thymidine phosphorylase due to the response in chemotherapy with TS-1 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.4 Homo sapiens
-
-
-
2.4.2.10 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.4 oral squamous cell carcinoma cell
-
 Homo sapiens
-
2.4.2.10 oral squamous cell carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.4 5'-deoxy-5-fluorouridine + phosphate
-
 Homo sapiens 5-fluorouracil + 5-deoxy-D-ribose 1-phosphate
-
 ?
2.4.2.10 orotate + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens orotidine 5'-phosphate + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.10 OPRT
-
 Homo sapiens
2.4.2.10 orotate phosphoribosyl transferase
-
 Homo sapiens