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Literature summary extracted from

  • Chan, S.I.; Yu, S.S.
    Controlled oxidation of hydrocarbons by the membrane-bound methane monooxygenase: the case for a tricopper cluster (2008), Acc. Chem. Res., 41, 969-979.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.18.3 additional information pMMO with the full complement of copper ions does not require methanobactin for activity Methylococcus capsulatus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.18.3 membrane integral membrane protein Methylococcus capsulatus 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.18.3 Cu2+ multicopper enzyme, contains 3 Cu2+ ions per trimer, contains 13.6 copper atoms per protein complex Methylococcus capsulatus
1.14.18.3 Zn2+ contains one Zn2+ ion in the transmembrane domain Methylococcus capsulatus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.18.3 28328
-
 1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus
1.14.18.3 29733
-
 1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus
1.14.18.3 42785
-
 1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus

Organism

EC Number Organism UniProt Comment Textmining
1.14.18.3 Methylococcus capsulatus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.18.3 2 1-butene + 2 reduced acceptor + 2 H+ + 2 O2
-
 Methylococcus capsulatus 3-buten-2-ol + 1,2-epoxybutane + 2 acceptor + 2 H2O
-
 ?
1.14.18.3 2 butane + 2 reduced acceptor + 2 H+ + 2 O2
-
 Methylococcus capsulatus 1-butanol + 2-butanol + 2 acceptor + 2 H2O
-
 ?
1.14.18.3 2 pentane + 2 reduced acceptor + 2 H+ + 2 O2
-
 Methylococcus capsulatus 1-pentanol + 2-pentanol + 2 acceptor + 2 H2O
-
 ?
1.14.18.3 2 propane + 2 reduced acceptor + 2 H+ + 2 O2
-
 Methylococcus capsulatus 1-propanol + 2-propanol + 2 acceptor + 2 H2O
-
 ?
1.14.18.3 3 cis-2-butene + reduced acceptor + H+ + O2
-
 Methylococcus capsulatus meso-2,3-dimethyloxirane + acceptor + H2O
-
 ?
1.14.18.3 3,3,3-trifluoropropene + reduced acceptor + H+ + O2
-
 Methylococcus capsulatus 3,3,3-trifluoro-1,2-epoxypropane + acceptor + H2O
-
 ?
1.14.18.3 methane + reduced acceptor + H* + O2
-
 Methylococcus capsulatus methanol + acceptor + H2O
-
 ?
1.14.18.3 trans-2-butene + reduced acceptor + H+ + O2
-
 Methylococcus capsulatus 2,3-dimethyloxirane + acceptor + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.18.3 heterotrimer 1 * 42785 + 1 * 29733 + 1 * 28328, MALDI-TOF mass spectrometry Methylococcus capsulatus

Synonyms

EC Number Synonyms Comment Organism
1.14.18.3 particulate methane monooxygenase
-
 Methylococcus capsulatus
1.14.18.3 pMMO
-
 Methylococcus capsulatus