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Literature summary extracted from

  • Shim, J.S.; Kwon, Y.Y.; Hwang, J.K.
    The effects of panduratin A isolated from Kaempferia pandurata on the expression of matrix metalloproteinase-1 and type-1 procollagen in human skin fibroblasts (2008), Planta Med., 74, 239-244.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.7 epigallocatechin-3-gallate
-
 Homo sapiens
3.4.24.7 additional information panduratin A, isolated from Kaempferia pandurata, suppresses MMP-1 expression and enhances the expression of type-1 procollagen in UV-irradiated skin fibroblasts, overview Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.7 membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.7 collagen I + H2O Homo sapiens degradation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.7 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.7 fibroblast
-
 Homo sapiens
-
3.4.24.7 skin
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.7 additional information
-
 quantitative MMP-1 expression analysis by RT-PCR in presence or absence of enzyme inhibitors Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.7 collagen I + H2O degradation Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.7 matrix metalloproteinase-1
-
 Homo sapiens
3.4.24.7 MMP-1
-
 Homo sapiens