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Literature summary extracted from

  • Citak Kurt, A.N.; Ustundag, B.; Akarsu, S.; Kurt, A.; Yilmaz, E.; Ocal, C.; Aygun, A.D.
    Cord blood prolidase activity correlates with gestational age and birth weight (2008), Neonatology, 94, 110-112.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.13.9 diagnostics cord blood prolidase activity may be a good indicator of fetal maturation and gestational age Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.13.9 cytosol
-
 Homo sapiens 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.13.9 Mn2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.13.9 additional information Homo sapiens prolidase, a specific iminopeptidase involved in collagen turnover, is especially active in growing tissues, the final step of collagen degradation is mediated by prolidase, the cytosolic enzyme specifically splits iminopeptides with C-terminal proline or hydroxyproline, which together contribute 21% of collagen ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.9 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.9 blood cord blood Homo sapiens
-
3.4.13.9 additional information prolidase is especially active in growing tissues Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.13.9 additional information
-
 cord blood prolidase activity is 41.4 U/l in term infants and 35.2 U/l in preterm infants Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.9 Gly-Pro + H2O
-
 Homo sapiens Gly + Pro
-
 ?
3.4.13.9 additional information prolidase, a specific iminopeptidase involved in collagen turnover, is especially active in growing tissues, the final step of collagen degradation is mediated by prolidase, the cytosolic enzyme specifically splits iminopeptides with C-terminal proline or hydroxyproline, which together contribute 21% of collagen Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.13.9 prolidase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.13.9 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.13.9 8
-
 assay at Homo sapiens