EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.105 | co-expression of Rhomboid-1 with growth factor Spitz in COS-7 cells | Drosophila melanogaster |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.21.105 | membrane | intramembrane enzyme with 6 transmembrane segments | Drosophila melanogaster | 16020 | - |
3.4.21.105 | membrane | intramembrane enzyme with 6 transmembrane segments | Escherichia coli | 16020 | - |
3.4.21.105 | membrane | intramembrane enzyme with 6 transmembrane segments | Haemophilus influenzae | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.105 | growth factor Spitz + H2O | Drosophila melanogaster | Rhomboid-1 | ? | - |
? | |
3.4.21.105 | additional information | Drosophila melanogaster | regulation, overview | ? | - |
? | |
3.4.21.105 | additional information | Escherichia coli | regulation, overview | ? | - |
? | |
3.4.21.105 | additional information | Haemophilus influenzae | regulation, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.105 | Drosophila melanogaster | - |
- |
- |
3.4.21.105 | Escherichia coli | - |
gene glpG | - |
3.4.21.105 | Haemophilus influenzae | P44783 | gene glpG | - |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.4.21.105 | cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, catalytic dyad id formed by S201 and H254, structure-function modeling | Escherichia coli | |
3.4.21.105 | cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, catalytic dyad id formed by S201 and H254, structure-function modeling | Haemophilus influenzae | |
3.4.21.105 | cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains | rhomboid structure and catalytic mechanism, structure-function modeling | Drosophila melanogaster |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.105 | growth factor Spitz + H2O | Rhomboid-1 | Drosophila melanogaster | ? | - |
? | |
3.4.21.105 | additional information | regulation, overview | Drosophila melanogaster | ? | - |
? | |
3.4.21.105 | additional information | regulation, overview | Escherichia coli | ? | - |
? | |
3.4.21.105 | additional information | regulation, overview | Haemophilus influenzae | ? | - |
? | |
3.4.21.105 | additional information | structure-function relationship, substrate entry, overview | Escherichia coli | ? | - |
? | |
3.4.21.105 | additional information | structure-function relationship, substrate entry, overview | Haemophilus influenzae | ? | - |
? | |
3.4.21.105 | additional information | structure-function relationship, substrate entry, Rhomboid active-site topology, overview | Drosophila melanogaster | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.21.105 | More | molecular structure, alternative conformations for the putative gating helix 5 of GlpG, GlpG forms a water-filled cavity on the extracellular side of GlpG, with the catalytic serine at its base, overview | Escherichia coli |
3.4.21.105 | More | molecular structure, alternative conformations for the putative gating helix 5 of GlpG, overview | Haemophilus influenzae |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.105 | GlpG | - |
Escherichia coli |
3.4.21.105 | GlpG | - |
Haemophilus influenzae |
3.4.21.105 | rhomboid-1 | - |
Drosophila melanogaster |