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Literature summary extracted from

  • Sterk, M.; Mueller, J.; Hemphill, A.; Mueller, N.
    Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin (2007), Microbiology, 153, 4150-4158.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.2.1 daidzein enzyme is a major daidzein-binding protein Giardia intestinalis
3.2.2.1 formononetin
-
 Giardia intestinalis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.2.1 0.07
-
 Inosine pH 7.3, 37°C Giardia intestinalis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.2.1 40000
-
 x * 40000, SDS-PAGE Giardia intestinalis

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.1 Giardia intestinalis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.1 adenosine + H2O best substrate Giardia intestinalis D-ribose + adenine
-
 ?
3.2.2.1 cytidine + H2O about 20% of the rate with adenosine Giardia intestinalis cytosine + D-ribose
-
 ?
3.2.2.1 guanosine + H2O about 80% of the rate with adenosine Giardia intestinalis D-ribose + guanine
-
 ?
3.2.2.1 inosine + H2O rate of hydrolysis similar to adenosine Giardia intestinalis hypoxanthine + D-ribose
-
 ?
3.2.2.1 uridine + H2O about 15% of the rate with adenosine Giardia intestinalis D-ribose + uracil
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.2.1 ? x * 40000, SDS-PAGE Giardia intestinalis

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.2.2.1 0.0038
-
 daidzein pH 7.3, 37°C Giardia intestinalis
3.2.2.1 0.011
-
 formononetin pH 7.3, 37°C Giardia intestinalis