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Literature summary extracted from
- Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080) (2007), Mar. Biotechnol., 8, 593-599.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.24.35 | drug development | MMP-9 is a target for therapeutic treatment | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.35 | chitooligosaccharides | different molecular weight, inhibit both MMP-9 expression and activity, especially 1- to 3-kDa chitooligosaccharides, chitooligosaccharides-I in HT-1080 cells | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.35 | Gelatin + H2O | Homo sapiens | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.35 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.35 | HT-1080 cell | a fibrosarcoma cell line | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.35 | Gelatin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.24.35 | Gelatin + H2O | gelatin zymography | Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.35 | matrix metalloproteinase-9 | - |
Homo sapiens |
| 3.4.24.35 | MMP-9 | - |
Homo sapiens |
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