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Literature summary extracted from

  • Van Ta, Q.; Kim, M.M.; Kim, S.K.
    Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080) (2007), Mar. Biotechnol., 8, 593-599.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.24.35 drug development MMP-9 is a target for therapeutic treatment Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.35 chitooligosaccharides different molecular weight, inhibit both MMP-9 expression and activity, especially 1- to 3-kDa chitooligosaccharides, chitooligosaccharides-I in HT-1080 cells Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.35 Gelatin + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.35 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.35 HT-1080 cell a fibrosarcoma cell line Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.35 Gelatin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.35 Gelatin + H2O gelatin zymography Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.35 matrix metalloproteinase-9
-
 Homo sapiens
3.4.24.35 MMP-9
-
 Homo sapiens