Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Schram, K.; Wong, M.M.; Palanivel, R.; No, E.K.; Dixon, I.M.; Sweeney, G.
    Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts (2008), J. Mol. Cell. Cardiol., 44, 874-881.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.80 additional information MT1-MMP expression at the cell surface is increased by leptin Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.80 epigallocatechin-3-gallate
-
 Rattus norvegicus
3.4.24.80 Tissue inhibitor of metalloproteinase-1 TIMP-1 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.80 cell surface
-
 Rattus norvegicus 9986
-
3.4.24.80 membrane
-
 Rattus norvegicus 16020
-
3.4.24.80 additional information expression analysis of MT1-MMP in cell culture Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.80 additional information Rattus norvegicus MT1-MMP activates MMP-2 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.80 Rattus norvegicus
-
 1- to 3-day old Sprague-Dawley rat pups
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.80 cell culture neonatal cardiac myofibroblasts Rattus norvegicus
-
3.4.24.80 fibroblast neonatal cardiac myofibroblasts Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.80 additional information MT1-MMP activates MMP-2 Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.80 MT1-MMP
-
 Rattus norvegicus