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Literature summary extracted from

  • Vepsaelaeinen, S.; Parkinson, M.; Helisalmi, S.; Mannermaa, A.; Soininen, H.; Tanzi, R.E.; Bertram, L.; Hiltunen, M.
    Insulin-degrading enzyme is genetically associated with Alzheimers disease in the Finnish population (2007), J. Med. Genet., 44, 606-608.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.56 IDE gene is localized on chromosome 10q24, genotyping of IDE in the Finnish population, overview Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.4.24.56 additional information genotyping of single nucleotide polymorphisms in the IDE gene in Finnish patients with Alzheimer's disease, SNPs rs4646953 and rs4646955 to be associated with Alzheimer's disease, the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.56 insulin + H2O Homo sapiens degradation ?
-
 ?
3.4.24.56 additional information Homo sapiens the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.56 Homo sapiens
-
 Finnish population
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.56 insulin + H2O degradation Homo sapiens ?
-
 ?
3.4.24.56 additional information the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.56 IDE
-
 Homo sapiens
3.4.24.56 Insulin-degrading enzyme
-
 Homo sapiens