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Literature summary extracted from

  • Rykl, J.; Thiemann, J.; Kurzawski, S.; Pohl, T.; Gobom, J.; Zidek, W.; Schlueter, H.
    Renal cathepsin G and angiotensin II generation (2006), J. Hypertens., 24, 1797-1807.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.20 angiotensin I + H2O Sus scrofa
-
angiotensin II + ?
-
?
3.4.21.20 angiotensin I + H2O Homo sapiens
-
angiotensin II + ?
-
?
3.4.21.20 angiotensinogen + H2O Sus scrofa
-
angiotensin I + ?
-
?
3.4.21.20 angiotensinogen + H2O Homo sapiens
-
angiotensin I + ?
-
?
3.4.21.20 angiotensinogen + H2O Sus scrofa
-
angiotensin II + ?
-
?
3.4.21.20 angiotensinogen + H2O Homo sapiens
-
angiotensin II + ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.20 Homo sapiens P08311 precursor
-
3.4.21.20 Sus scrofa Q95284 fragment
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.20 native enzyme from kidney by anion exchange and hydroxyapatite chromatography, lentil lectin affinity chromatography, and gel filtration or chymostatin-antipain affinity chromatography, to homogeneity Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.20 kidney
-
Sus scrofa
-
3.4.21.20 kidney
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.20 angiotensin I + H2O
-
Sus scrofa angiotensin II + ?
-
?
3.4.21.20 angiotensin I + H2O
-
Homo sapiens angiotensin II + ?
-
?
3.4.21.20 angiotensinogen + H2O
-
Sus scrofa angiotensin I + ?
-
?
3.4.21.20 angiotensinogen + H2O
-
Homo sapiens angiotensin I + ?
-
?
3.4.21.20 angiotensinogen + H2O
-
Sus scrofa angiotensin II + ?
-
?
3.4.21.20 angiotensinogen + H2O
-
Homo sapiens angiotensin II + ?
-
?

Subunits

EC Number Subunits Comment Organism
3.4.21.20 More MALDI-TOF mass spectrometrical peptide finger printing, overview Sus scrofa