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Literature summary extracted from

  • Galicka, A.; Nazaruk, J.
    Stimulation of collagen biosynthesis by flavonoid glycosides in skin fibroblasts of osteogenesis imperfecta type I and the potential mechanism of their action (2007), Int. J. Mol. Med., 20, 889-895.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.13.9 apigenin-7-O-glucuronide stimulates the enzyme and collagen biosynthesis in osteogenesis imperfecta type I cells, overview Homo sapiens
3.4.13.9 pectolinarin stimulates the enzyme and collagen biosynthesis in osteogenesis imperfecta type I cells, overview Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.13.9 Mn2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.13.9 additional information Homo sapiens the enzyme catalyzes the final step of collagen degradation and plays an important role in collagen biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.9 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.9 Gly-Pro + H2O
-
 Homo sapiens Gly + Pro
-
 ?
3.4.13.9 additional information the enzyme catalyzes the final step of collagen degradation and plays an important role in collagen biosynthesis Homo sapiens ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.13.9 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.13.9 7.8
-
 assay at Homo sapiens