Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • McCaig, C.; Duval, C.; Hemers, E.; Steele, I.; Pritchard, D.M.; Przemeck, S.; Dimaline, R.; Ahmed, S.; Bodger, K.; Kerrigan, D.D.; Wang, T.C.; Dockray, G.J.; Varro, A.
    The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori (2006), Gastroenterology, 130, 1754-1763.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.23 additional information infections with Helicobacter pylori increases MMP-7 expression in the stomach epithelium, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.23 Collagen + H2O Homo sapiens
-
 ?
-
 ?
3.4.24.23 insulin-like growth factor binding protein-5 + H2O Homo sapiens in the medium of gastric myofibroblasts, knockdown of IGFBP-5 abolished the myofibroblast proliferation response to MMP-7, overview ?
-
 ?
3.4.24.23 additional information Homo sapiens MMP-7 is involved in signaling between epithelial cells and a key stromal cell type, the myofibroblast, via insulin-like growth factor binding protein-5 cleavage and IGF-II release, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.23 Homo sapiens P09237
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.23 epithelium MMP-7 is uniquely produced in epithelia Homo sapiens
-
3.4.24.23 gastric gland
-
 Homo sapiens
-
3.4.24.23 myofibroblast primary Homo sapiens
-
3.4.24.23 stomach
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.23 Collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.23 insulin-like growth factor binding protein-5 + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.23 insulin-like growth factor binding protein-5 + H2O in the medium of gastric myofibroblasts, knockdown of IGFBP-5 abolished the myofibroblast proliferation response to MMP-7, overview Homo sapiens ?
-
 ?
3.4.24.23 additional information MMP-7 is involved in signaling between epithelial cells and a key stromal cell type, the myofibroblast, via insulin-like growth factor binding protein-5 cleavage and IGF-II release, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.23 Matrix metalloproteinase-7
-
 Homo sapiens
3.4.24.23 MMP-7
-
 Homo sapiens