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Literature summary extracted from

  • Kim, T.D.; Song, K.S.; Li, G.; Choi, H.; Park, H.D.; Lim, K.; Hwang, B.D.; Yoon, W.H.
    Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer (2006), BMC Cancer, 6, 211.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.73 55000
-
 x * 55000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.73 additional information Homo sapiens the enzyme is involved in colorectal cancer invasion and metastasis ?
-
 ?
3.4.21.73 plasminogen + H2O Homo sapiens
-
 plasmin + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.73 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.73 colon very low enzyme content Homo sapiens
-
3.4.21.73 colonic carcinoma cell
-
 Homo sapiens
-
3.4.21.73 colorectal cancer cell
-
 Homo sapiens
-
3.4.21.73 additional information uPA is expressed differentially in colon and rectal cancers, expression analysis, overview Homo sapiens
-
3.4.21.73 rectal carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.73 additional information the enzyme is involved in colorectal cancer invasion and metastasis Homo sapiens ?
-
 ?
3.4.21.73 plasminogen + H2O
-
 Homo sapiens plasmin + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.73 ? x * 55000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.21.73 uPA
-
 Homo sapiens
3.4.21.73 Urokinase-type plasminogen activator
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.21.73 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.73 8
-
 assay at Homo sapiens