EC Number | Application | Comment | Organism |
---|---|---|---|
3.4.21.9 | medicine | human TRAIL is a candidate for clinical application in cancer therapy, activity is lost in some forms of recombinant TRAIL, refolding of thioredoxin/TRAIL and cleavage by enteropeptidase yield a biological active anticancer agent | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.9 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.9 | thioredoxin-tumor necrosis factor-related apoptosis-inducing ligand fusion protein + H2O | trx/TRAIL | Homo sapiens | thioredoxin + tumor necrosis factor-related apoptosis-inducing ligand | enteropeptidase is used to cleave TRAIL from thioredoxin at enzyme-substrate molar ratio of 1 : 30,000 | ? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.9 | enteropeptidase | - |
Homo sapiens |
3.4.21.9 | enteropeptidase light chain | L-HEP | Homo sapiens |