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Literature summary extracted from

  • Chow, S.Y.; Williams, H.J.; Pennington, J.D.; Nanda, S.; Reibenspies, J.H.; Scott, A.I.
    Studies on taxadiene synthase: interception of the cyclization cascade at the verticillene stage and rearrangement to phomactatriene (2007), Tetrahedron, 63, 6204-6209.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.17 for expression in Escherichia coli BL21DE3 cells Phoma sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.17 geranylgeranyl diphosphate Phoma sp.
-
 taxa-4,11-diene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.17 Phoma sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.17 7-desmethylgeranylgeranyl diphosphate product may be an artefact, but non is formed when enzyme is not present Phoma sp. (6E,10E)-11,15-dimethyl-3-methylidenehexadeca-1,6,10,14-tetraene + diphosphate
-
 ?
4.2.3.17 7-desmethylgeranylgeranyl diphosphate
-
 Phoma sp. (3E,7E,11S,12R)-4,11,12,15-tetramethylbicyclo[9.3.1]pentadeca-1(15),3,7-triene + diphosphate
-
 ?
4.2.3.17 7-desmethylgeranylgeranyl diphosphate
-
 Phoma sp. (1S,4E,8E,14R,15S)-1,8,14,15-tetramethylbicyclo[9.3.1]pentadeca-4,8,11-triene + diphosphate
-
 ?
4.2.3.17 geranylgeranyl diphosphate
-
 Phoma sp. taxa-4,11-diene + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.17 taxadiene synthase
-
 Phoma sp.