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Literature summary extracted from

  • Kim, M.; Im, Y.J.; Lee, J.H.; Eom, S.H.
    Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori (2006), Proteins, 63, 252-255.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.4.2.19 crystal structure of Hp-QAPRTase with bound quinolinic acid, nicotinic acid mononucleotide, and phthalic acid. Hp-QAPRTase crystals are grown at 20°C using the hanging drop vapor diffusion method Helicobacter pylori

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.19 pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate Helicobacter pylori essential enzyme in the NAD+ biosynthetic pathway nicotinate D-ribonucleotide + diphosphate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.19 Helicobacter pylori O25909
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.19 pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate essential enzyme in the NAD+ biosynthetic pathway Helicobacter pylori nicotinate D-ribonucleotide + diphosphate + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.2.19 hexamer Hp-QAPRTase forms a hexamer with a - trimer of dimers - configuration Helicobacter pylori

Synonyms

EC Number Synonyms Comment Organism
2.4.2.19 Hp-QAPRTase
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 Helicobacter pylori
2.4.2.19 type II quinolinic acid phosphoribosyltransferase
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 Helicobacter pylori