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Literature summary extracted from

  • Phillips, J.D.; Bergonia, H.A.; Reilly, C.A.; Franklin, M.R.; Kushner, J.P.
    A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda (2007), Proc. Natl. Acad. Sci. USA, 104, 5079-5084.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.37 porphomethene competitive inhibitor Homo sapiens
4.1.1.37 porphomethene competitive inhibitor Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.37 cytosol
-
 Mus musculus 5829
-
4.1.1.37 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.37 Homo sapiens
-
-
-
4.1.1.37 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.37 liver
-
 Mus musculus
-
4.1.1.37 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.37 Uroporphyrinogen III
-
 Mus musculus Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III
-
 Homo sapiens Coproporphyrinogen III + 4 CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.37 URO-D
-
 Mus musculus
4.1.1.37 URO-D
-
 Homo sapiens