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Literature summary extracted from
- Axonal transports of tripeptidyl peptidase II in rat sciatic nerves (2007), Neurochem. Int., 50, 236-242.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.4 | 1,10-phenanthroline | strongly inhibitory at 1 mM | Rattus norvegicus |  |
| 3.4.11.4 | Ala-Ala-Phe-chloromethyl ketone | 85-90% inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Ca2+ | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Cu2+ | strongly inhibitory at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | diisopropylfluorophosphate | strongly inhibitory at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | EDTA | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Fe2+ | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Hg2+ | strongly inhibitory at 0.1 mM | Rattus norvegicus | |
| 3.4.11.4 | iodoacetic acid | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Mg2+ | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Mn2+ | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | N-ethylmaleimide | partial inhibition at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | p-chloromercuriphenylsulfonic acid | strongly inhibitory at 1 mM | Rattus norvegicus | |
| 3.4.11.4 | Zn2+ | partial inhibition at 1 mM | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.4 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.11.4 | sciatic nerve | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.4 | Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | Ala-Ala-Phe + 7-amino-4-methylcoumarin | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.11.4 | EC 3.4.14.10 | formerly | Rattus norvegicus |
| 3.4.11.4 | TPPII | - |
Rattus norvegicus |
| 3.4.11.4 | tripeptidyl peptidase II | - |
Rattus norvegicus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.4 | 6 | 7.8 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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