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Literature summary extracted from

  • Andersson, M.K.; Pemberton, A.D.; Miller, H.R.; Hellman, L.
    Extended cleavage specificity of mMCP-1, the major mucosal mast cell protease in mouse - High specificity indicates high substrate selectivity (2008), Mol. Immunol., 45, 2548-2558.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.39 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.39 Ni-NAT agarose bead chromatography, heparin affinity chromatography, and gel filtration Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.39 BMMC cell
-
 Mus musculus
-
3.4.21.39 mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.39 atrial natriuretic peptide clearance receptor + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 cadherin-10 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 cadherin-13 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 collagen alpha-1(VI) chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 collagen alpha-1(XII) chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 desmocollin-3 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 integrin alpha-11 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 integrin alpha-3 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 integrin alpha-7 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 laminin alpha-3 chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 laminin alpha-4 chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 laminin alpha-5 chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 laminin gamma-1 chain + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 matrix metalloprotease 8 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 methoxy-succinyl-Arg-Ala-Tyr-4-nitroanilide + H2O high activity Mus musculus methoxy-succinyl-Arg-Ala-Tyr + 4-nitroaniline
-
 ?
3.4.21.39 additional information in position P1 a distinct preference for Phe and Ser is observed, in position P2 a high selectivity for Phe, Trp and Leu is detected, while P3 and P4 show specificity for aliphatic amino acids Mus musculus ?
-
 ?
3.4.21.39 protocadherin alpha-4 + H2O potential substrate Mus musculus ?
-
 ?
3.4.21.39 Vitronectin + H2O potential substrate Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.39 beta-chymase
-
 Mus musculus
3.4.21.39 MCP-1
-
 Mus musculus
3.4.21.39 mucosal mast cell protease
-
 Mus musculus