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Literature summary extracted from

  • Tomatsu, S.; Vogler, C.; Montano, A.M.; Gutierrez, M.; Oikawa, H.; Dung, V.C.; Orii, T.; Noguchi, A.; Sly, W.S.
    Murine model (Galns(tm(C76S)slu)) of MPS IVA with missense mutation at the active site cysteine conserved among sulfatase proteins (2007), Mol. Genet. Metab., 91, 251-258.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.1.6.4 C76S active site mutation, results in inactive enzyme Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.4 Mus musculus Q571E4 precursor
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.4 bone
-
 Mus musculus
-
3.1.6.4 bone marrow
-
 Mus musculus
-
3.1.6.4 brain
-
 Mus musculus
-
3.1.6.4 heart
-
 Mus musculus
-
3.1.6.4 kidney
-
 Mus musculus
-
3.1.6.4 liver
-
 Mus musculus
-
3.1.6.4 spleen
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.4 chondroitin sulfate + H2O
-
 Mus musculus chondroitin + sulfate
-
 ?
3.1.6.4 keratan sulfate + H2O
-
 Mus musculus keratan + sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.6.4 GALNS
-
 Mus musculus
3.1.6.4 N-acetylgalactosamine-6-sulfate sulfatase
-
 Mus musculus