BRENDA - Enzyme Database

The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement

Yau, S.; Wachsman, J.T.; Mol. Cell. Biochem. 1, 101-105 (1973)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
1.17.4.2
ATP
required
Bacillus megaterium
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.2
Hydroxyurea
20 mM, 20% inhibition
Bacillus megaterium
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.17.4.2
Mg2+
required
Bacillus megaterium
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.17.4.2
Bacillus megaterium
-
-
-
1.17.4.2
Bacillus megaterium KM / ATCC 13632
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.2
CDP + reduced dithiothreitol
-
681889
Bacillus megaterium
dCDP + oxidized dithiothreitol + H2O
-
-
-
?
1.17.4.2
CDP + reduced dithiothreitol
-
681889
Bacillus megaterium KM / ATCC 13632
dCDP + oxidized dithiothreitol + H2O
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.17.4.2
coenzyme B12
required
Bacillus megaterium
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
1.17.4.2
ATP
required
Bacillus megaterium
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.17.4.2
coenzyme B12
required
Bacillus megaterium
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.17.4.2
Hydroxyurea
20 mM, 20% inhibition
Bacillus megaterium
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.17.4.2
Mg2+
required
Bacillus megaterium
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.17.4.2
CDP + reduced dithiothreitol
-
681889
Bacillus megaterium
dCDP + oxidized dithiothreitol + H2O
-
-
-
?
1.17.4.2
CDP + reduced dithiothreitol
-
681889
Bacillus megaterium KM / ATCC 13632
dCDP + oxidized dithiothreitol + H2O
-
-
-
?