Literature summary extracted from

Alfano, R.W.; Leppla, S.H.; Liu, S.; Bugge, T.H.; Herlyn, M.; Smalley, K.S.; Bromberg-White, J.L.; Duesbery, N.S.; Frankel, A.E.
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells (2008), Mol. Cancer Ther., 7, 1218-1226.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.4.24.83	matrix metalloproteinase 2	-	Bacillus anthracis
3.4.24.83	matrix metalloproteinase 9	-	Bacillus anthracis

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.83	Bacillus anthracis	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.83	mitogen-activated protein kinase kinase + H2O	-	Bacillus anthracis	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.24.83	anthrax lethal factor	-	Bacillus anthracis

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Release 2023.1 (January 2023)